References Herbert V. Similar to cardiovascular disease, although the research has shown that vitamin B12 supplementation where homocysteine blood levels, this vitamin not translated into frrom come of cognitive decline. Cofactor F Replacement therapy for vitamin B12 deficiency: comparison between the sublingual and oral route. Please click the link in the email to reset your password. Staying Healthy Nutrition. Create an Account Sign in with Facebook. Naturally can u muscle pain early pregnancy suggest that supplemental calcium might help improve the vitamin B12 malabsorption does by b12 [ from, 97 ], but not qhere researchers agree [ 99 ].
Many people believe that B12 only comes from animal flesh and animal secretions i. Fungi, animals and plants are incapable of producing B12 on their own and must obtain it from outside sources. B12 is synthesized by bacteria and is therefore found in areas of bacterial growth, namely dirt and soil. Humans have been getting their B12 from the dirt for hundreds of thousands of years by eating plants that still had bits of soil on them.
Have a question? Vitamin B12 is a water-soluble vitamin that is naturally present in some foods, added to others, and available as a dietary supplement and a prescription medication. Vitamin B12 exists in several forms and contains the mineral cobalt [ ], so compounds with vitamin B12 activity are collectively called “cobalamins”. Methylcobalamin and 5-deoxyadenosylcobalamin are the forms of vitamin B12 that are active in human metabolism [ 5 ]. Vitamin B12 is required for proper red blood cell formation, neurological function, and DNA synthesis [ ]. Vitamin B12 functions as a cofactor for methionine synthase and L-methylmalonyl-CoA mutase. Methionine synthase catalyzes the conversion of homocysteine to methionine [ 5, 6 ]. Methionine is required for the formation of S-adenosylmethionine, a universal methyl donor for almost different substrates, including DNA, RNA, hormones, proteins, and lipids.