Tag Archives: trial

GSK, Bayer stand by CureVac following ‘disappointing’ COVID-19 vaccine trial flop

CureVac’s late-stage COVID-19 vaccine trial flop clearly showed that not all pandemic shots are alike. But where does that leave the German biotech and its Big Pharma partners? For one, ongoing collaborations with Bayer and GlaxoSmithKline aren’t going anywhere for now, the companies said following the interim results drop late Wednesday.  CureVac reported that its first-gen pandemic shot, known… Read More »

NIH ‘very concerned’ about serious side effect in AstraZeneca coronavirus vaccine trial

“The highest levels of NIH are very concerned,” said Dr. Avindra Nath, intramural clinical director and a leader of viral research at the National Institute for Neurological Disorders and Stroke, an NIH division. “Everyone’s hopes are on a vaccine, and if you have a major complication the whole thing could get derailed.” A great deal… Read More »

AstraZeneca’s COVID-19 vaccine production partner Emergent not likely to suffer if trial hold sticks: analysts

AstraZeneca was humming right along with its partnered COVID-19 vaccine with the University of Oxford before a sudden trial hold threw its plans into disarray. So what does that uncertainty mean for AstraZeneca’s expectant manufacturing partners on the shot? For at least one, it could be no issue at all.  Despite a major commitment from… Read More »

Coronavirus vaccine with 50% or more efficacy would be a ‘game changer,’ says trial investigator

A coronavirus vaccine that is safe and at least 50% effective would be a “game changer” in battling the pandemic, according to a doctor who is serving as an investigator for Moderna‘s clinical trials. “Developing vaccines against respiratory virus is incredibly difficult. If you think about the flu vaccine that we use every year, it’s… Read More »

Promising treatment to slow kidney disease doesn’t prove out in clinical trial

Historically, half or more of people with type 1 diabetes develop kidney disease, which frequently progresses to kidney failure requiring hemodialysis or a kidney transplant for survival. The high rate of this diabetic complication has dropped slightly in recent years, with the advent of better ways to control blood glucose (sugar) levels and improved blood… Read More »