Tag Archives: essential

Essential Reads: Neurosteroids, Allopregnanolone and Vulnerability to Depression in Women

Essential Reads: Neurosteroids, Allopregnanolone and Vulnerability to Depression in Women Women are twice as likely as men to suffer from a depressive disorder.  In addition, they are vulnerable to mood disorders associated with reproductive functioning, specifically premenstrual dysphoric disorder, perinatal depression, and perimenopausal depression. There is strong evidence to indicate that biological factors (genetic vulnerability,… Read More »

Essential Reads: Zuranolone for Postpartum Depression

In 2019, the Food and Drug Administration (FDA) approved brexanolone, marketed by Sage Therapeutics as Zulresso, as a treatment for postpartum depression (PPD).  As a neurosteroid, brexanolone represents a novel approach to the treatment of postpartum mood disorders.  One of the most exciting things about brexanolone is the rapidity of the response, with the initial… Read More »

Essential Reads: A Clinical Guide for the Diagnosis and Treatment of PMDD

In an evidence-based review published in 2012, Laura Wakil, Samantha Meltzer-Brody, and Susan Girdler present a thorough review of premenstrual dysphoric disorder (PMDD), reviewing its diagnosis and treatment options.  The information provided is clear and provides an excellent framework for understanding PMDD.  In addition, this article includes a section on the association between PMS/PMDD and… Read More »